About Dr. Isaac George,
Heart Valve Surgeon

Hello! My name is Dr. Isaac George and I am a cardiac surgeon having graduated from Duke University School of Medicine in 2001. To date, I have performed approximately over 10,000 cardiac surgeries, of which over 6,000 involved heart valve procedures. I regularly perform surgery at Columbia University Medical Center. Read more...

Video About Dr. Isaac George

33 Patient Reviews for
Dr. George

"Columbia Presbyterian Hospital was highly recommended by our family doctor. I initially consulted Dr. Takayama who referred me to Dr. George for a TAVR heart valve procedure.

From our initial consultation, to testing, to surgery, and finally to post-operative care, Dr. George and his team were wonderful.

The TAVR procedure was explained by Dr. George in understandable terms. Testing was done by experienced technicians and results were available quickly. We also met with Dr. Vahl who further explained and was part of the surgical team. Seeing their familiar faces in the operating room was very reassuring. Maureen Gaine, Nurse Practitioner, was very helpful and supportive throughout the process.

The Columbia connect app was easy to use. Notes from the doctor visits, test results, appointment information and more were easy to access.

Highly recommended. My sincere thanks to all who took such good care of me."

-- M Conn, Aortic Valve, Transcatheter, 05/20/2025

"Dr. George was extremely thorough and competent. He has an excellent bedside manner and the surgery was completely successful."

-- Sal Paonessa, Mitral Valve, Valve Repair, Robotic Surgery, 03/11/2025

> See 31 more patient testimonials

My Specialities &
Clinical Interests

My heart surgery specialties include:

  • Valve Surgery: Aortic, Mitral, and Tricuspid Repair and Replacement (Standard and Minimally Invasive), Transcatheter Valve Surgery (TAVR): Percutaneous, TransAortic, Transapical Approach for Aortic and Mitral valve disease
  • Aortic Aneurysm Surgery: Aortic Root, Aortic Arch, and Endovascular Hybrid Thoracic Aortic Stenting
  • Hybrid Surgery: Valve+PCI, Robotic MIDCAB+PCI, Complex Reoperative Valve+PCI

In addition, I have research and clinical interests specific to:

  • Myostatin Dependent Regulation of Cardiomyocyte Growth and Atrophy Signaling
  • TGF-Beta regulation and Signaling in Patients with Non-Syndromic Aortic Aneurysms
  • Mechanisms of valve calcification in Surgical versus Transcatheter Valve Replacement

Education, Training & Certificates

Dr. Isaac George, heart surgeon, graduated from Duke University School of Medicine in 2001.

After medical school, Dr. George completed an extensive 10-year training program in surgery, cardiac surgery and interventional cardiology. From 2001 to 2008, Dr. George completed an Internship, a General Surgery Residency, and a Cardiothoracic Surgery Residency at New York Presbyterian Hospital - Columbia University Medical Center in New York.

Then, Dr. George was a Post-Doctoral Clinical Fellow in Cardiothoracic Surgery and a Fellow in Cardiothoracic Surgery at New York Presbyterian Hospital - Columbia University Medical Center from 2008 to 2010. To broaden his cardiac specialties, Dr. George completed a Ventricular Assist Device/Cardiac Transplant Fellowship, Minimally Invasive Cardiac Surgery, in 2011, and an Interventional Cardiology / Hybrid Cardiac Surgery Fellowship at New York Presbyterian Hospital - Columbia in 2012.

In July, 2012, Dr. George became an Assistant Professor of Surgery and later an Assistant Professor of Medicine. In 2019, Dr. George was promoted to Associate Professor of Surgery.

Dr. George is board certified by the American Board of Surgery and the American Board of Thoracic Surgery.

During his career, Dr. George has received numerous honors and awards including:

* Duke University Comprehensive Cancer Center Fellowship
* Pi Tau Sigma, Mechanical Engineering Honor Society
* New Era Cardiac Surgery Conference Scholarship (2004)
* Blakemore Award - Best Resident Research Award, Columbia University- College of Physicians and Surgeons (2006, 2007, 2008)

Schedule Appointment
with Dr. Isaac George, MD

To schedule an appointment with Dr. George, you can:

The office of Dr. George is located at 177 Fort Washington Avenue, New York City, NY 10032. To get driving directions to this office, please click the map below.



> Click for driving directions to Dr. George’s office.

Watch Educational Video with Dr. Isaac George

Learn about heart valve surgery from Dr. George in this video:

  • Stroke Risk & Transcatheter Aortic Valve Replacement (TAVR) with Dr. Isaac George

News & Online References Featuring Dr. Isaac George

Here is the latest news featuring Dr. Isaac George:

Page last updated: July 28, 2025